Brookhaven's NanoBrook Omni instrument combines the best technology from our particle/protein sizer and zeta potential analyzer in to one powerful and accurate solution for sizing and zeta potential analysis. Measure samples in nearly every possible suspension environment from high salts such as PBS and sea water to organic solvents and of course aqueous solutions. Particle and protein sizing, with the highest sensitivity, utilizing three measurement angles for truly unbiased measurement results. The NanoBrook Omni utilizes a backscattering angle as well as 90° and 15°.
NanoBrook 90Plus ZETA
Brookhaven's NanoBrook 90Plus Zeta instrument combines our NanoBrook 90Plus and NanoBrook ZetaPlus instruments into one versatile package for routine sizing and zeta potential analysis. It employs Dynamic Light Scattering (DLS) for particles/molecules size and Electrophoretic Light Scattering (ELS) for particles/molecules surface charge evaluation. This package not only allows rapid measurements of the effective size and zeta potential of samples, but also provides further information on multimode distribution in size and surface charge in polydisperse samples. Based on the proven technologies of Brookhaven, the NanoBrook 90Plus Zeta guarantees excellent mobility measurement performance in aqueous suspensions and low salt environments.
NanoBrook 90Plus PALS
Brookhaven's NanoBrook 90Plus PALS instrument combines our NanoBrook 90Plus and NanoBrook ZetaPALS instruments in to one powerful package for sizing and zeta potential analysis. With over a decade of proven records in diverse applications, Brookhaven's pioneer Phase Analysis Light Scattering (PALS) technology remains a step ahead of the competition. This package delivers unparalleled zeta potential (surface charge) measurement sensitivity and accuracy. It also provides unique real-time (in-situ) monitoring capability for electrophoretic response of particles/molecules under an electric field, a valuable tool ONLY from Brookhaven for delicate biological entities like proteins and exosomes. It has been successfully utilized in nearly every possible suspension environment from high salts such as PBS and sea water to organic solvents and of course aqueous solutions.
For measurements of very low mobilities, the NanoBrook ZetaPALS is the answer. The only answer! With concepts developed at Bristol University and Brookhaven Instruments, the NanoBrook ZetaPALS determines zeta potential using Phase Analysis Light Scattering: A technique that is up to 1,000 times more sensitive than traditional light scattering methods based on the shifted frequency spectrum. Electrostatic repulsion of colloidal particles is often the key to understanding the stability of any dispersion. A simple, easy measurement of the electrophoretic mobility "even in nonpolar liquids" yields valuable information. Measurements made in water and other polar liquids are easy and fast with the NanoBrook ZetaPlus. Such measurements cover the range of typically ± (6 to 100) mV, corresponding to mobilities of ± 0.5-8x10-8 m 2 /V·s. The NanoBrook ZetaPALS covers this full range, of course, and extends it by a factor of 1000 in sensitivity!
The NanoBrook ZetaPlus is the simplest and most accurate particle electrophoresis system available. This revolutionary instrument has been designed to eliminate the short coming inherent in other zeta potential instruments. The ZetaPlus software is simple and intuitive to operate but yet offers flexibility and a full range of means for those that whish to tune their experiments to specific circumstances. The unique cell configuration eliminates the electroosmotic effect: No stationary levels, no alignment, and no calibration are required; as evidenced by the excellent agreement with NIST1980, a standard reference material. The NanoBrook ZetaPlus uses low cost, disposable sample cells. There is no assembly or maintenance required: Cross contamination is eliminated. Glass and quartz cells are available optionally. The same basic cell design is used with the NanoBrook 90Plus Zeta, ZetaPALS, 90Plus PALS, and Omni.
The BI-ZTU, autotitrator option for the NanoBrook zeta potential analyzers is ideal for automatic determination of the isoelectric point, the IEP, of colloidal materials. Four pumps provide unparalled flexibility for optimizing reagent use. The dramatic savings of reduced labor costs will also encourage larger scale studies that will produce more valuable results. In addition, the BI-ZTU can be used to evaluate the effect of salt concentration on zeta potential. Also, the surfactant costs can be minimized. Use the BI-ZTU to find the minimum concentration at which the zeta potential does not significantly change.
Surface Zeta Potential Electrode
The Surface Zeta Potential feature allows the user to measure the electrical charge on materials like coated glass, plastic, tape, or other flexible surfaces. A series of measurements are taken on probe particles at different distances from a surface and the Surface Zeta Potential is calculated as shown above.
Particle Solution Software
Designed to operate with NanoBrook series particle characterisation instruments, Particle Solutions software suite integrates characterisation of 5 different particle measurement technologies - DLS, SLS, Phase Analysis Light Scattering (PALS), micro-Rheology and Molecular Weight Determination in one package. The new version of this popular software suite for NanoBrook series particle characterisation instruments includes a host of useful new features. New features include Laboratory Information Management System support, Surface Zeta Potential measurement capability, Multimodal Size Distribution refinement, Health Mode post-measurement analysis, and Statistical Process Control. Safeguarding the investment of existing users - measurements made with earlier versions of the software can be imported into Particle Solutions, and then analyzed with the same powerful tools.
Note: Particle Solutions is only usable with Brookhaven Instruments light scattering systems.